Molecule by Pud&Mun 01 Perfume- Iso E Super (100ml)

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Belsito; etal. (2013). "A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients. RIFM Expert Panel". Food and Chemical Toxicology. 62: S1-44. doi: 10.1016/j.fct.2013.09.033. PMID 24246175. a b US 3929677,Hall, John B.&Sanders, James Milton,"Perfume composition and perfume articles containing one isomer of an octahydrotetramethyl acetonaphthone",issued 1975 No data were available regarding chemical disposition, metabolism, or toxicokinetics; acute, short-term, subchronic, or chronic toxicity; synergistic or antagonistic activity; reproductive or teratological effects; carcinogenicity; genotoxicity; or immunotoxicity. [5] Scientific Committee on Consumer Safety (2011). "Annex I: Clinical evidence regarding sensitisation to individual fragrance chemicals and to natural extracts" (PDF). SCCS Opinion on fragrance allergens in cosmetics. European Union. p.63. SCCS/1459/11.

OTNE is therefore not classified as a PBT or vPvB substance [7] for the EU or any other global criteria. Stagnant water, charcoal, semen... 10 smells that changed the perfume industry". The Telegraph . Retrieved 2017-06-21. Ethanone, 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-Tetramethyl-2-Naphthalenyl)- (Iso-E Super®; OTNE) M990091". OTNE has been detected in surface water at levels of 29–180ng/L, [15] [16] These values are well below the Predicted No Effect Concentration (PNEC) and as a result the overall environmental risk ratio (also referred to as RCR or PEC/PNECS) is determined to be below 1. [7] Regulatory status [ edit ] OTNE is the abbreviation for the fragrance material with Chemical Abstract Service ( CAS) numbers 68155-66-8, 54464-57-2 and 68155-67-9 and EC List number 915-730-3. It is a multi-constituent isomer mixture containing:

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The fragrance Molecule 01 (Escentric Molecules, 2005) is a specific isomer of Iso E Super, by the company IFF. [19] Its partner fragrance Escentric 01 contains Iso E Super along with ambroxan, pink pepper, green lime with balsamic notes like benzoin mastic and incense.

Bester, K. (Nov 2008). "Surface water concentrations of the fragrance compound OTNE in Germany--a comparison between data from measurements and models". Chemosphere. 73 (8): 1366–72. Bibcode: 2008Chmsp..73.1366B. doi: 10.1016/j.chemosphere.2008.06.057. PMID 18715610. Iso E Super, an aroma-chemical with its own distinct nature, goes beyond being a traditional fragrance and creates a captivating effect. With its almost transparent color, it exudes a subtle and elusive sweet cedarwood-like scent, evoking a masculine, woodsy, and musky aroma. It has earned the reputation of being the invisible fragrance and has been likened to the modern-day Love Potion No.9. The reason behind this is its unique ability to mimic the action of human pheromones. While not a pheromone itself, Iso E Super has the remarkable effect of catching the attention of others, who find themselves unable to pinpoint the exact reason for their intrigue. It creates an air of mystery that leaves people fascinated but unable to articulate why. In 2014 the US National Toxicology Program ( NTP) conducted a 13-week repeat dose toxicity study and found no adverse effects. [17]Iso E Super is a very common perfume ingredient, providing a sandalwood-like and cedarwood-like fragrance, in soap, shampoo, perfumes, detergents, fabric fresheners, antiperspirants or deodorants, and air fresheners. It is also used as a tobacco flavoring (at 200–2000ppm), as a plasticizer and as a precursor for the delivery of organoleptic and antimicrobial compounds. [5] Production [ edit ] OTNE is classified as H410 Very toxic to aquatic life with long-lasting effects ( EU-CLP) or R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment (EU DSD). [7] Iso E Super is a molecule that hovers close to the skin to create an indefinable aura around the wearer. OTNE is registered on all major chemical inventories (US, Japan, China, Korea, Philippines, and Australia) and has been EU REACH registered in 2010. [7]

Scognomiglio; etal. (2013). "Fragrance material review on 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone (OTNE)". Food and Chemical Toxicology. 62: S120-32. doi: 10.1016/j.fct.2013.08.056. PMID 24246180. Given the sensitization classification of OTNE, and its use in fragrances, the International Fragrance Association (IFRA) has published safe use levels for OTNE in consumer products, which have been in effect since August 2009. [14] Environmental data [ edit ] Several health related studies have been conducted on OTNE, and based on these studies, OTNE has been determined to be safe under the current conditions of use. [12] [13] Our Molecule Scent 01 contains a proprietary mixture of Iso E Super, that focuses on gamma isomers, which results in increased allure.

The measured Bio Concentration Factor (BCF) is 391L/kg, which is well below the EU limit of 2000 and US limit of 1000 for Bioaccumulation (B) classification. The LogKow for OTNE has been measured to be 5.65. [7] Discover the captivating nature of Iso E Super, an aroma-chemical that transcends traditional fragrances. Experience the allure of its sweet cedarwood-like scent and embrace the intrigue it brings to both the wearer and those around them. The distinction of Iso E Super lies in its design as an aroma-chemical rather than a traditional fragrance. Ordinary fragrances are crafted to project themselves over a wide radius, while Iso E Super is specifically formulated to cling to the skin, effortlessly oscillating between moments of opulence and simplicity. This duality allows it to be at times distinctly noticeable and at other times undetectable, creating an intriguing and ever-changing olfactory experience. The wearer may perceive a subtle, velvety, and woody note that momentarily fades away, only to resurface after some time, enhancing the fragrance's allure and complexity.