Dolovent - Contributes to The Normal Function of The Nervous System, a Reduction in Tiredness & Fatigue and Normal Psychological Function

Product Information

There are several CoQ10 supplements on the market, and it can be difficult to determine which one is the most effective for migraines. Look for a supplement that uses ubiquinol, which is the active form of CoQ10, and has a high absorption rate. Are there any side effects of taking CoQ10 for migraines? Overall, we highly recommend Dolovent to anyone looking for a natural supplement to help prevent migraines. Dolovent Linpharma Magnesium, B2, CoQ10 Dietary Supplement for Brain Health – 2 Bottles CoQ10's effect has not been studied to the extent of other natural substances (such as magnesium), but the research that has been conducted shows and associates use of CoQ10 over four months - enhanced energy and a substantial feeling of well being. BIOFLAVONOIDS & OTHER ELEMENTS Food supplements should not be used as a substitute for a varied diet. Do not exceed the recommended daily dose. Keep out of reach of children. Pregnant women and children should use the product under medical supervision. Mainstream medical research has documented that a deficiency in magnesium, Vitamin B2 and coenzyme Q10 can play a role - maintaining healthy blood flow to the brain. Correcting this dietary deficiency is a challenge since food alone cannot supply the clinical levels these micronutrients need to achieve normal brain energy levels.* This is why the clinical-strength Dolovent formulation was created.

Over the past few years, among the substances that could potentially be used for migraine treatment, particular attention has been paid to the so-called nutraceutics [ 42]. This group includes, among others, vitamins (e.g., riboflavin), dietary supplements with, for example, coenzyme Q10, and alpha lipoic acid [ 42, 43]. Antioxidants supplied with food prevent oxidative stress by inhibiting initiation, propagation, and the oxidative chain reaction itself. Other mechanisms of action of antioxidants from food are, among others, the scavenging of free radicals, molecular oxygen quenching, and acting as reductants in oxidative reactions [ 44]. Ongoing studies on the mechanisms of migraine pathogenesis have contributed to advances in research on possible treatment modalities. In the present state of knowledge, it is believed that the pathogenesis of migraine, in all its complexity, is determined by, among others, genetic and epigenetic factors as well as the effect of numerous environmental factors [ 43]. Furthermore, as mentioned above, oxidative stress is considered to play a significant role in migraine pathogenesis. The modulation of the effect of oxidative stress is possible by providing antioxidants [ 43]. Additionally, the agents used so far in the prevention of migraine indeed show some antioxidative action [ 43]. Dolovent supports normal brain energy levels* by helping to maintain normal levels of magnesium, vitamin B2, coenzyme Q10, and other essential vitamins, minerals and trace elements that are all targeted at stabilizing cellular and brain energy and overall health. The way Dolovent does this is by delivering the clinical strength of these micronutrients needed to support normal levels of cellular and brain energy.We highly recommend the Horbäach CoQ10 supplement for those looking for a powerful antioxidant to help with migraines. Horbäach manufacturers the supplement with trusted ingredients, superior quality, and 100% guaranteed purity and potency. In agreement with the above result, the evaluation of efficacy of the preventive treatment was better for verum than for placebo. The difference was statistically significant (p=0.01). 18.2% of the patients in the active group rated the efficacy as very good, none in the placebo group. Nearly 50% (47.3%) of the patients rated the efficacy “very good” or “good” which was twice as many as in the placebo group. Also, the number of patients rating efficacy as poor was higher in the placebo group.

This supplement supports cell energy production by helping to produce ATP, the primary source of cellular energy. The maximal intensity of migraine pain per migraine day during the last month of the 3-month treatment was compared between treatment groups by an ANCOVA with the maximal intensity of migraine pain during the baseline period as baseline covariate.The burden of disease measured by HIT-6 sum scores for the end of treatment was compared between treatment groups by an ANCOVA with the burden of disease sum scores for the start of treatment as baseline covariate. Understanding health conditions, and how scientific developments throughout the world enable people to manage their conditions better allows us to source targeted solutions which optimise and improve an individual’s health and quality of life. Take two capsules twice daily, once in the morning and once in the evening with or after a meal or as directed by your health practitioner. Magnesium works in balance with calcium, whereby calcium causes muscle contraction, and magnesium causes muscle relaxation. Recently, the use of curcumin in migraine treatment has been increasingly considered by scientists. Bulboacă et al. conducted a study on migraine treatment in which they compared the effect of sumatriptan (ST) administered alone and ST used together with curcumin. The study was conducted using a rat model of migraine induced by nitro-glycerine. Curcumin was administered intravenously in the form of a) alcoholic solution (diluted in saline), and b) liposomes due to reduced gastrointestinal absorption of curcumin [ 66]. The authors reported the antioxidative effect of curcumin (decrease in MDA concentration, reduced production of RNS, reduction of TOS, and an increase in TAS) for each dose and form applied (solution/liposomes). However, greater antioxidative properties of curcumin were observed when it was administered in the form of liposomes. The authors attribute the obtained results to curcumin’s ability to scavenge hydroxyl or peroxyl radicals, direct interaction with peroxide radical anion, and inhibition of the activity of κB nuclear transcription factors (NF κBs), which are involved in the transcription of proinflammatory factors [ 66]. The same scientists also conducted another study using a rat model of migraine (also induced by nitro-glycerine) to compare the effect of naproxen and curcumin solution on the parameters of oxidative stress and pain sensations [ 67]. Administration of liposomal curcumin resulted in a decreased MDA concentration, reduced nitrogen oxide (NO) synthesis, reduced TOS values, and reduction of nociception. When curcumin and naproxen were administered together, the antioxidative mechanisms were found to be improved (thiol increase and higher total antioxidant capacity, TAC) in comparison with naproxen used alone. However, the authors indicated that a greater antioxidative effect was observed in subjects who were administered curcumin in the form of liposomes [ 67]. Yet another study confirmed the positive antioxidative and analgesic effect of curcumin as compared with treatment using propranolol and indomethacin [ 68] ( Table 2).