Joined in 2023 
82 
63 About this deal
The usual dose for adults and children is 1 drop into the affected eye(s), 4 times a day, or as needed. The letter to the GPshould state clearly which eye lubricants have already been tried by the patient and also whether the VisuXL ® eye gel is to be used in addition to OR instead of the previous eye product(s) and which one where appropriate. Close your eye. Gently press your finger over the inside corner of your eye (over the eyelid) for about 1 minute. This helps to keep the drop in your eye.
The tear break-up time in patients treated with Tears Again was increased greater than that of those treated with Liposic at 6 weeks Optive Plus ®(carboxymethylcellulose 0.5%, glycerine 1%, castor oil 0.25%) is also non-formulary - see above. The equivalent formulary product containing mineral oil is Systane Balance.
7. Cautions with other medicines
The frequency of adverse reactions documented during clinical trials is given. The frequency is defined as follows: Very Common (≥ 1/10); Common (≥1/100, <1/10); Uncommon (≥1/1,000, <1/100); Rare (≥1/10,000, <1/1,000); Very Rare (<1/10,000), not known (cannot be estimated from the available data). For use only in patients with moderate to severe dry eye with corneal epithelial staining and on the recommendation of a specialist. Ans : In most of the cases, the average time taken by this medication to reach its peak effect is around 1 day to 1 week. Please consult your doctor for the time period you need to use this medication. Soothe ® (Bausch & Lomb Incorporated, Bridgewater, NJ, USA) is a lipid-based artificial tear. A pair of separate studies aimed to elucidate its effects on the LLT within the tear film. The first study evaluated the effectiveness of Soothe ® versus Refresh Optive ®. Enrollment included 41 patients with a LLT under 70 nm in both eyes and baseline visual acuity greater than 20/70. Each patient received a drop of Soothe ® in one eye and Refresh Optive ® in the contralateral eye. A custom-designed lipid layer interferometer quantified the LLT at 1, 5, and 15 minutes after application. Both artificial tears increased the LLT from a baseline of 61.5±1.6 nm ( P<0.001), with a mean LLT of 83.2±3.6 nm for Refresh Optive ® and 121.5±3.8 nm for Soothe ® ( P<0.001). 47 Discontinue use and consult your doctor if you experience eye pain, change in vision, continued redness or irritation or if condition worsens.
Sodium Carboxymethyl cellulose-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from: ALLERGAN is one of the leading companies in the field of ophthalmology - and has been for over 60 years. Continuous research regularly leads to new products. A supporting prescribing guideline may be requested which must have been agreed by the relevant secondary care trust DTCs and approved by the Nottinghamshire APC.
FAQs
Optive 0.5% Eye Drops may cause side effects such as eye pain, irritation, and vision disturbances. These symptoms usually subside on their own. However, consult your doctor if these symptoms stay for a long time or if they become severe. Avoid driving or operating machines if you experience these symptoms. Allergan funded a project studying the efficacy of Refresh Tears ®, Refresh Ultra ®, and Refresh Optive ® in relieving the signs and symptoms of dry eye. 43 A total of 37 participants completed the study; 18 with a history of dry eye and 19 controls without a history of dry eye. In this three-way cross-over study, each patient used each artificial tear formulation for 2 weeks while TBUT, tear evaporation, osmolarity, tear structure, and patient symptoms were evaluated. All patients with a history of dry eye experienced improvement in both their signs and symptoms of dry eye with all formulations ( P<0.05). In the control group, Refresh Optive ® and Refresh Ultra ® treatment resulted in a decreased rate of evaporation, significantly greater than Refresh Tears ® on cross-group comparison. Refresh Tears ® was the only formulation observed to decrease tear osmolarity in the control group ( P<0.05). No other statistical difference appeared on cross-group analysis. Preservative free eye drop preparations can be recommended by ophthalmology specialists when a patient is on multiple different eye drops to minimise ocular exposure to preservative.
To be used in patients where sodium hyaluronate alone no longerprovides adequate control in moderate to severe dry eye, in accordance with the Dry Eye Treatment guidance. A third study analyzing Refresh and Systane products compared the effects of Refresh Liquigel ® and Systane ® on corneal staining and symptomatic improvement in 60 patients. 30 A reduced sum score of corneal staining and a reduction of corneal staining from baseline were only observed in the Refresh Liquigel ® group ( P=0.008 and P=0.019, respectively). Patient’s tear preference and comfort were also analyzed in this study; however, patients were not blinded to the artificial tear assigned. Using one eye for each artificial tear, patient preference was recorded 5 minutes after application with 36% of patients preferring Refresh and 24% preferring Systane. Limited value may be drawn from the subjective component of this study since unilateral symptoms may have been present in the study participants. For use only in patients with moderate to severe dry eye with corneal epithelial stains and on the recommendation of a specialist. Ans : This medication is generally used once or twice a day. It is advised to consult your doctor before the usage, as the frequency also depends on the patient's condition.Patients who suffer from severe dry eyes tend to use artificial tears often throughout the day. This leads to the eye being exposed to high levels of preservative, causing toxicity in around 9% of patients. Patients using artificial tears >4-6 times per day should use apreservative-free preparation. Posttherapeutic subjective comfort results revealed Systane Ultra outperformed Refresh Optive, GenTeal, and Blink Tears Ans : This medication is advised to be consumed orally. If you take it on an empty stomach, it might upset the stomach. Please consult the doctor before using it. Patients should be encouraged to manage both dry eyes and sore eyes by implementing some self-care measures such as good eyelid hygiene and avoidance of environmental factors alongside treatment.
Questionnaire revealed 68.9% of Hylo-Comod users and 78.5% of Systane users had improvement of symptoms by switching to Refresh Optive. TBUT also improved with Refresh
4. How and when to use carmellose sodium
No new patients to receive prescriptions in primary care. Patients already receiving Red Medicines in primary care should be handled on a case by case basis with the support of the Medicines Optimisation team. The Hylo-Tear® (0.1%)& Hylo-Forte® (0.2%) brands are manufactured in a COMOD device which may prove difficult to use in those with dexterity problems. These products have a six month expiry once opened (if used in hospital a 14 day expiry remains)
Great Deal 
New Comment