Broccoli Sprout Extract by LLS | Contains Activated Sulforaphane | 60 Capsules | 18,000mg of Whole Plant Equivalent per Serving | Sulforaphane Supplement | Potent Antioxidant Content

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Tříska J, Balík J, Houška M, Novotná P, Magner M, Vrchotová N, Híc P, Jílek L, Thorová K, Šnurkovič P, Soural I. Factors Influencing Sulforaphane Content in Broccoli Sprouts and Subsequent Sulforaphane Extraction. Foods. 2021 Aug 19;10(8):1927. doi: 10.3390/foods10081927. PMID: 34441704; PMCID: PMC8394606. Moreover, cruciferous vegetables also contain a variety of other nutrients known to have important health effects (e.g., vitamin C, vitamin K, carotenoids, and flavonoids) ( Manchali et al., 2012). As such, it is difficult to separate the action of glucosinolates from these other compounds when determining the results of food-based cruciferous vegetable interventions. Further, when these vegetables are consumed as part of a particular dietary pattern, there may be other factors influencing the effect of glucosinolates consumed (e.g., influences on metabolism and gut microbiota). This idea is also relevant to observational studies, where other diet components could influence the observed associations between glucosinolate-rich vegetables and particular health outcomes. Therefore, future large-scale human trials utilizing standardized, reproducible protocols, and appropriate glucosinolate doses that reflect realistic habitual intake are needed to further elucidate the benefits of cruciferous vegetables and related compounds. One of the key benefits of sulforaphane from broccoli sprouts is its antioxidant ability. [13] Antioxidants protect cells from oxidative stresses that can occur on a daily basis, such as positive stresses from exercise, sun exposure, digesting, or focusing hard on a task, and negative stresses like consumption of processed foods and pesticides, pollution, cleaning products, radiation, medications, alcohol consumption and exposure to industrial chemicals. When we exercise, oxidative stress naturally occurs, and consuming the correct nutrients to support your recovery is vital. The myrosinase reaction and the interconversion of sulforaphane and erucin. The glucosinolates glucoraphanin and glucoerucin are hydrolyzed by β-thioglucosidases (myrosinases) to give unstable aglycones and liberate glucose. Depending on the reaction conditions, a variety of reactive products can be formed, the most common of which are the isothiocyanates (sulforaphane and erucin) and their corresponding nitriles. In mammals, glucoraphanin is also taken up from the gut to the liver where it is interconverted to its reduced analog, glucoerucin, as is sulforaphane to erucin. R 1=4-(methylsulfinyl)butane; R 2=4-(methylthio)butane. for Kidney Research, Children’s Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, NSW, Australia

The sulforaphane found in broccoli may help alleviate H. pylori infections by activating enzymes that help the stomach heal faster (x). Lowers Cholesterol Levels Work in an industry that involves frequent use of cleaning products, fumes, or work in a factory environment Broccoli sprout extract can be easily taken in supplement form on a daily basis. Taking 2 capsules daily with food provides a powerful dose of sulforaphane to help lower inflammation, protect cells from oxidative stress, prevent type 2 diabetes and cardiovascular disease, and enhance exercise recovery. If you have a diagnosed thyroid condition, please speak to your healthcare provider before supplementing with broccoli sprout extract. Key TakeawaysTechnically, foods don’t actually contain sulforaphane, they contain glucoraphanin, which when ingested, stimulates the body to produce sulforaphane. Sulforaphane is a phytonutrient. Phytonutrients are a group of chemicals found in plant foods that lower inflammation, protect cells from oxidative damage, and have potent anti-cancer and anti-heart disease effects. As well as sulforaphane, other particularly powerful phytonutrients include quercetin and curcumin. [4] Broccoli sprouts and broccoli sprout seeds are two of the best known sources of glucoraphanin, which stimulates the production of sulforaphane to help your body detoxify. Other cruciferous vegetables like cabbage, cauliflower and brussels sprouts also contain the precursor to sulforaphane, but in lower levels than broccoli sprouts. Key Benefits of Sulforaphane Mild side effects have been associated with sulforaphane supplements, such as an increase in gas, constipation, and diarrhea ( 17, 29). Jaishankar M, Tseten T, Anbalagan N, Mathew BB, Beeregowda KN. Toxicity, mechanism and health effects of some heavy metals. Interdiscip Toxicol. 2014 Jun;7(2):60-72. doi: 10.2478/intox-2014-0009. Epub 2014 Nov 15. PMID: 26109881; PMCID: PMC4427717.

we don't necessarily feel immediately. We pay a lot of attention to the quality of our ingredients, their Along with vitamin K, the choline in broccoli can help maintain and improve cognition. This has been measured in cognitive-performance tests and in healthy white-matter volumes of the brain (x). When considering the role of glucosinolates for musculoskeletal health, sulforaphane has been studied most extensively in animal models. Historically, the understanding of the effects of glucosinolates on skeletal muscle comes from trials of their application in animal production settings, with results indicating that although growth performance may be affected, muscle had an improved antioxidant status and fatty acid profile ( Drażbo et al., 2019; Skugor et al., 2019). When sulforaphane was provided to male Wistar rats for 3days prior to performing exhaustive exercise, sulforaphane served as an indirect antioxidant in skeletal muscle, as measured by decreased tissue total antioxidant capacity in the vastus lateralis muscle. It was concluded that sulforaphane plays a vital role in modulating the muscle redox environment; ultimately creating favorable effects on muscle ( Malaguti et al., 2009). It was reported that type 2 diabetic mice receiving sulforaphane injections over 4week had greater grip strength, lean mass, and gastrocnemius mass ( Wang M. et al., 2020). These diabetic mice also presented with improved skeletal muscle fiber organization after sulforaphane treatment. It was proposed that sulforaphane may downregulate the expression of inflammatory and apoptotic associated proteins. Sulforaphane was also suggested to play a role in regulating mRNA levels of anti-inflammatory and oxidative related genes. Collectively, it was concluded that sulforaphane treatment could be protective against skeletal muscle disease in mice with type 2 diabetes.

Given the positive actions of glucosinolates are largely related to anti-inflammatory and antioxidant mechanisms, the consumption of cruciferous vegetables and their glucosinolates may also have beneficial outcomes on other health conditions. Although there are few studies investigating the impact of certain cruciferous vegetables on other chronic conditions, such as obesity, future studies are needed to further investigate the role of glucosinolates. Author Contributions Kubo, E., Chhunchha, B., Singh, P. et al.Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stress. Sci Rep 7, 14130 (2017). https://doi.org/10.1038/s41598-017-14520-8 May protect against brain damage. According to animal studies, sulforaphane may have the potential to improve recovery and reduce mental decline after a brain injury ( 24, 25, 26).