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Regaine for Men Extra Strength Scalp Foam 5 Percent w/w Cutaneous Foam Minoxidil , 3 Month's Supply Easy to Ese Foam, 73 ml (Pack of 3)

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The systemic absorption of minoxidil from a 5% foam formulation has been estimated in a pharmacokinetic study in subjects with androgenetic alopecia, which included 5% topical solution as a comparator. This demonstrated that in men, the systemic absorption of minoxidil from twice daily application of 5% minoxidil foam was about half of that observed with 5% minoxidil solution. The mean steady state AUC (0-12 hr) and Cmax for 5% minoxidil foam, 8.81 ng·hr/mL and 1.11 ng/mL, respectively, were both approximately 50 % of AUC (0-12 hr) and Cmax of the 5% solution, 18.71 ng·hr/mL and 2.13 ng/mL, respectively. The time to maximum minoxidil concentration (Tmax) for the 5% foam, 5.42 hr, was similar to Tmax for the 5% solution, 5.79 hr.

Minoxidil is not effective for everyone. If you feel there is no improvement after 12 months of using the solution, you should stop using it. If you are using minoxidil foam, you should stop using it after 16 weeks if there is no improvement. Pump spray applicator: this is useful for large areas. Aim the pump at the centre of the bald area, press once and spread with fingertips over the entire bald area. Repeat for a total of 6 times to apply a dose of 1 ml. Avoid breathing spray mist. Another study has shown that systemic absorption of Minoxidil 5% foam is around half of that of Minoxidil 5% liquid [3]. Systemic absorption refers to the amount of Minoxidil that reaches organs and tissue beyond the scalp.In this study Regaine for Men Extra Strength Scalp Solution 5% w/v Cutaneous Solution was compared to the product vehicle without the minoxidil active ingredient and also to 2% minoxidil cutaneous solution.

It’s also important to remember that this type of hair loss treatment will not work for everyone. Regaine Extra Strength states in its Patient Information leaflet that it should be used by men aged 18-65, and that it is most likely to be effective in people who fall into the following categories: Helps Stop Hereditary Hair Loss - An estimated 8 million men have hair loss problems in the UK. Regaine Foam is scientifically proven to help reverse hereditary hair loss.The safety of topical minoxidil from clinical trials data is based on data from 7 placebo-controlled randomised clinical trials in adults evaluating either 2% or 5% minoxidil solution, and two placebo-controlled randomised clinical trials in adults evaluating a 5% foam formulation. As a peripheral vasodilator minoxidil enhances microcirculation to hair follicles. The Vascular Endothelial Growth Factor (VEGF) is stimulated by minoxidil and VEGF is presumably responsible for the increased capillary fenestration, indicative of a high metabolic activity, observed during the anagen phase.

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Medical Problems As with any medicine, Minoxidil comes with some mild side effects such as mild skin irritations. However if you experience any side effects you should stop using Regaine and tell your doctor or pharmacist. Animal reproduction toxicity studies in rats and rabbits have shown signs of maternal toxicity and a risk to the foetus at exposure levels that are very high compared to those, intended for human exposure. A low, albeit remote, risk of foetal harm is possible in humans.Inactive ingredients: Butane, butylated hydroxytoluene, cetyl alcohol, citric acid, glycerol, isobutane, lactic acid, polysorbate 60, propane, purified water, stearyl alcohol, ethanol anhydrous. Minoxidil comes as a lotion, liquid or foam, normally in a strength of 2% or 5%. The higher concentration is usually only recommended for use by men and is labelled by Regaine as Extra Strength for Men. To have any positive effect upon hair loss, minoxidil must be applied at least once a day, every day for as long as treatment is desired. A lined aluminium pressurised container with a child-resistant plastic or polypropylene overcap, containing 60 gram of product. Some consumers reported increased hair shedding upon initiation of therapy with Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam. This is most likely due to minoxidil's action of shifting hairs from the resting telogen phase to the growing anagen phase (old hairs fall out as new hairs grow in their place). This temporary increase in hair shedding generally occurs two to six weeks after beginning treatment and subsides within a couple of weeks. If shedding persists (> 2 weeks), users should stop using Regaine for Men Extra Strength Scalp Foam 5% w/w Cutaneous Foam and consult their doctor.

REGAINE products and treatments are for hereditary hair loss. REGAINE for Men Extra Strength Scalp Foam 5% w/w Cutaneous foam, REGAINE for Women Once a Day Scalp Foam 5% w/w Cutaneous Foam, REGAINE for Men Extra Strength Scalp Solution 5% w/v Cutaneous Solution, REGAINE for Women Regular Strength contain Minoxidil. Always read the label. UK/RE/18-12646 Regaine for Men Extra Strength Scalp Solution 5% w/v Cutaneous Solution may therefore be considered by men who wish to achieve a faster onset and greater degree of hair regrowth than would be expected through the use of Regaine Regular Strength. Regaine For Women Once A Day Foam was developed following 6 years of research and was tested in clinical studies across 5 countries and is the only clinically proven foam for women to regrow hair. As for all medicines, minoxidil isn't suitable for everyone. Talk to your GP or pharmacist for adviceRegaine has been shown to encourage hair regrowth in as little as eight weeks, however this could be up to 16 weeks for some people. You also must bear in mind that the first six weeks of using Regaine may see a temporary increase in hair loss. What happens if I miss a dose of Minoxidil? It may take twice-daily applications for 8 weeks or more before evidence of hair growth can be expected. Users should discontinue treatment if there is no improvement seen after 16 weeks. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially: The primary efficacy criterion was non-vellus hair count in a 1.0cm 2 reference area of affected scalp. The mean changes observed in this parameter in these studies were significantly in favour of active treatment. A significant dose effect was also demonstrated. The results are summarized in the following table:

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