Marching Powder

Product Information

Cascio MJ, Jen KY (January 2018). "Cocaine/levamisole-associated autoimmune syndrome: a disease of neutrophil-mediated autoimmunity". Current Opinion in Hematology. 25 (1): 29–36. doi: 10.1097/MOH.0000000000000393. PMID 29211697. S2CID 23795272. Room R, Reuter P (January 2012). "How well do international drug conventions protect public health?". Lancet. 379 (9810): 84–91. doi: 10.1016/s0140-6736(11)61423-2. PMID 22225673. S2CID 23386203. The international treaties have also constrained national policy experimentation because they require nation states to criminalise drug use Bonkovsky HL, Mehta S (February 2001). "Hepatitis C: a review and update". Journal of the American Academy of Dermatology. 44 (2): 159–182. doi: 10.1067/mjd.2001.109311. PMID 11174373. Pure cocaine is prepared by neutralizing its compounding salt with an alkaline solution, which will precipitate non-polar basic cocaine. It is further refined through aqueous-solvent liquid–liquid extraction.

Ries RK, Miller SC, Fiellin DA (2009). Principles of addiction medicine. Lippincott Williams & Wilkins. p.137. ISBN 978-0-7817-7477-2. Archived from the original on 4 April 2014 . Retrieved 5 January 2014. Exhilaration and lasting euphoria, which in no way differs from the normal euphoria of the healthy person. You perceive an increase of self-control and possess more vitality and capacity for work. In other words, you are simply normal, and it is soon hard to believe you are under the influence of any drug. Long intensive physical work is performed without any fatigue. This result is enjoyed without any of the unpleasant after-effects that follow exhilaration brought about by alcoholic beverages. No craving for the further use of cocaine appears after the first, or even after repeated taking of the drug. [175]Martin RT (October 1970). "The role of coca in the history, religion, and medicine of South American Indians". Economic Botany. 24 (4): 422–438. doi: 10.1007/BF02860746. S2CID 34523519. InChI=1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1 Y Hamdan AL, Sataloff RT, Hawkshaw MJ (2022). "Topical Anesthesia in Office-Based Laryngeal Surgery". Office-Based Laryngeal Surgery. USA: Springer. pp.123–137. doi: 10.1007/978-3-030-91936-8_6. ISBN 978-3-030-91935-1. For those enamored of the glitzy life, coke—snow, blow, nose candy, Bolivian Marching Powder—became the drug. The first synthesis and elucidation of the structure of the cocaine molecule was by Richard Willstätter in 1898. [133] It was the first biomimetic synthesis of an organic structure recorded in academic chemical literature. [167] [168] The synthesis started from tropinone, a related natural product and took five steps.

In 1879, Vassili von Anrep, of the University of Würzburg, devised an experiment to demonstrate the analgesic properties of the newly discovered alkaloid. He prepared two separate jars, one containing a cocaine-salt solution, with the other containing merely saltwater. He then submerged a frog's legs into the two jars, one leg in the treatment and one in the control solution, and proceeded to stimulate the legs in several different ways. The leg that had been immersed in the cocaine solution reacted very differently from the leg that had been immersed in saltwater. [169] Jeevan Vasagar: cocaine-based "wonder drug" tested on concentration camp inmates". Amphetamines.com. 19 November 2002. Archived from the original on 27 February 2011 . Retrieved 15 January 2011. Calipari ES, Ferris MJ, Jones SR (January 2014). "Extended access of cocaine self-administration results in tolerance to the dopamine-elevating and locomotor-stimulating effects of cocaine". Journal of Neurochemistry. 128 (2): 224–32. doi: 10.1111/jnc.12452. PMC 3947316. PMID 24102293. In a study of cocaine users, the average time taken to reach peak subjective effects was 14.6minutes. [52] Any damage to the inside of the nose is due to cocaine constricting blood vessels — and therefore restricting blood and oxygen/nutrient flow — to that area. How much did you do last night? Two grams? I like the old marching powder, Jon, but I prefer to give myself a day or two off after a binge.’Jenkins AJ, Llosa T, Montoya I, Cone EJ (February 1996). "Identification and quantitation of alkaloids in coca tea". Forensic Science International. 77 (3): 179–189. doi: 10.1016/0379-0738(95)01860-3. PMC 2705900. PMID 8819993. Czykanski M (30 December 2015). "Cocaine Metabolites in Hair". Chemistry Views . Retrieved 22 July 2019. Valdez LM, Taboada J, Valdez JE (June 2015). "Ancient Use of Coca Leaves in the Peruvian Central Highlands". Journal of Anthropological Research. 71 (2): 231–258. doi: 10.3998/jar.0521004.0071.204. S2CID 163842955. Sunday Telegraph Astonishing real-life story of a Brit drug smuggler banged up in Bolivia's most notorious jail.

Martell BA, Mitchell E, Poling J, Gonsai K, Kosten TR (July 2005). "Vaccine pharmacotherapy for the treatment of cocaine dependence". Biol. Psychiatry. 58 (2): 158–64. doi: 10.1016/j.biopsych.2005.04.032. PMID 16038686. S2CID 22415520. a b Goldstein RA, DesLauriers C, Burda AM (January 2009). "Cocaine: history, social implications, and toxicity--a review". Disease-a-Month. 55 (1): 6–38. doi: 10.1016/j.disamonth.2008.10.002. PMID 19081448. Frazer KM, Richards Q, Keith DR (August 2018). "The long-term effects of cocaine use on cognitive functioning: A systematic critical review". Behavioural Brain Research. 348: 241–262. doi: 10.1016/j.bbr.2018.04.005. PMID 29673580. S2CID 4992738. Casciani D (4 June 2015). "Cocaine in sewage: London tops league table". BBC News. Archived from the original on 4 June 2015 . Retrieved 4 June 2015.Usage is particularly prevalent among this demographic: 4% to 7% of males have used cocaine in the last year in Spain, Denmark, the Republic of Ireland, Italy, and the United Kingdom. The ratio of male to female users is approximately 3.8:1, but this statistic varies from 1:1 to 13:1 depending on country. [152] Dwyer C, Sowerby L, Rotenberg BW (August 2016). "Is cocaine a safe topical agent for use during endoscopic sinus surgery?". The Laryngoscope (Review). 126 (8): 1721–1723. doi: 10.1002/lary.25836. PMID 27075241. Pergolizzi JV, Magnusson P, LeQuang JA, Breve F, Varrassi G (April 2021). "Cocaine and Cardiotoxicity: A Literature Review". Cureus. 13 (4): e14594. doi: 10.7759/cureus.14594. ISSN 2168-8184. PMC 8136464. PMID 34036012. Coca herbal infusion (also referred to as coca tea) is used in coca-leaf producing countries much as any herbal medicinal infusion would elsewhere in the world. The free and legal commercialization of dried coca leaves under the form of filtration bags to be used as "coca tea" has been actively promoted by the governments of Peru and Bolivia for many years as a drink having medicinal powers. In Peru, the National Coca Company, a state-run corporation, sells cocaine-infused teas and other medicinal products and also exports leaves to the U.S. for medicinal use. [128]

Leete E, Marion L, Spenser ID (October 1954). "Biogenesis of hyoscyamine". Nature. 174 (4431): 650–1. Bibcode: 1954Natur.174..650L. doi: 10.1038/174650a0. PMID 13203600. S2CID 4264282.Not quite as much fun as the real Halston, since Mr. McGregor was smoking green-tea cigarettes instead of Trues, snorting sugary, vitamin-like Inositol instead of Bolivian marching powder and, due to Covid restrictions, conjuring disco fever with just 48 extras in the Studio 54 scenes. Drug Fact Sheet: Cocaine" (PDF). Drug Enforcement Agency. Archived (PDF) from the original on 21 June 2020 . Retrieved 17 June 2022. Sophisticated drug subs are the latest tool drug runners are using to bring cocaine north from Colombia, it was reported on 20 March 2008. Although the vessels were once viewed as a quirky sideshow in the drug war, they are becoming faster, more seaworthy, and capable of carrying bigger loads of drugs than earlier models, according to those charged with catching them. [213] Sales to consumers Cocaine adulterated with fruit flavoring Hoye TR, Bjorklund JA, Koltun DO, Renner MK (January 2000). "N-methylputrescine oxidation during cocaine biosynthesis: study of prochiral methylene hydrogen discrimination using the remote isotope method". Organic Letters. 2 (1): 3–5. doi: 10.1021/ol990940s. PMID 10814231. In October 2010 it was reported that the use of cocaine in Australia has doubled since monitoring began in 2003. [190]